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KMID : 0351619740150020203
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Kyungpook Medical Journal
1974 Volume.15 No. 2 p.203 ~ p.210
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Effect of Postural Changes on Minute Ventilation, FRC and Pulmonary N₂ Clearance
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Abstract
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An attempt was made to study ventilatory and alveolar respiratory responses to the passive tilt. Anesthetized dogs were tilted from horizontal to upright (+90℃) and head down (-90℃) position.
Minute ventilation was decreased in the upright position and increased in the head down position comparing to that in the horizontal position. The FRC was increased in the upright position while decreased in the head down position.
The nitrogen clearance time was significantly prolonged in the upright position, and was approximately equal in the head down position to that in the horizontal position.
Lung N₂ clearance equivalent was slightly decreased in the upright position, whereas that was increased in the head down position.
Oxygen saturation percentage cf arterial blood decreased in the both upright and head down positions, and that of the mixed venous blood also decreased in the both positions.
From the above results, the ventilatory and alveolar respiratory compensation to the gravity in the passive tilting test was discussed, namely the decreased FRC was compensated by the increased minute ventilation and that an adequate per cent oxygen saturation of arterial blood was maintained in the head down position. On the contrary despite of the increased FRC, minute ventilation was diminished and lung clearance time was prolonged and that the per cent oxygen saturation of arterial blood was decreased in the upright position, and thus the respiratory response was not property compensated in the upright position.
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